South Carolina APRN license renewal: CE, fees, and prescriptive rules

NP, CRNA, CNM, CNS · Verified 2026-05-13

APRNs in South Carolina complete 30 CE hours every 2 years for board renewal. The APRN renewal fee is $105. The board is one of up to four clocks: your national certification and any DEA registration renew separately.

What the South Carolina Board of Nursing requires of APRNs

Requirement	Hours	Status
APRN Prescriptive Authority Pharmacotherapeutics	20 hrs	Required

Full renewal context (deadlines, grace period, audits): South Carolina nursing license renewal guide.

Prescriptive authority in South Carolina

Practice-authority and prescribing rules are the most state-specific (and fastest-changing) part of APRN practice: collaboration agreements, state controlled-substance registrations, and prescriber CE all vary. We have not yet verified South Carolina's rules against a board source, so confirm these with the South Carolina Board of Nursing before relying on any summary:

• Does prescribing require a collaboration or supervision agreement, and must it be re-filed at renewal?
• Is there a state controlled-substance registration separate from your DEA registration?
• Is there prescriber-specific pharmacology CE beyond the base requirement?
• Is current national certification a condition of APRN renewal?

The other three clocks

South Carolina has not enacted the APRN Compact (which is not yet operational anywhere). The Nurse Licensure Compact covers RN and LPN/VN licenses only, so multi-state APRN practice still means a separate APRN credential in each state. Your national certification (AANPCB, ANCC, NBCRNA, or AMCB) and any DEA registration renew on their own cycles, with their own CE math.

The four-clock guide: certification cycles, compact status, DEA and MATE

South Carolina APRN renewal FAQ

How many CE hours do APRNs need to renew in South Carolina?: APRNs in South Carolina complete 30 CE hours every 2 years for board renewal. That includes the APRN Prescriptive Authority Pharmacotherapeutics requirement of 20 hours. Your national certification keeps its own CE requirement on a separate clock.
What is the APRN renewal fee in South Carolina?: The South Carolina APRN renewal fee is $105, which differs from the RN fee; budget for both if you renew both credentials. Fees change, so confirm the current amount on the South Carolina Board of Nursing portal.
Can APRNs prescribe independently in South Carolina?: Practice-authority rules vary by state and change often. South Carolina's exact collaboration and prescribing rules are set by the South Carolina Board of Nursing; confirm them there before relying on any summary.
Does South Carolina require a state controlled-substance registration on top of the DEA?: Some states require a state controlled-substance registration separate from your federal DEA registration; others do not. South Carolina's rule is set by the board and state law; confirm before prescribing.
Is South Carolina in the APRN Compact?: No. South Carolina has not enacted the APRN Compact, and the compact itself is not yet operational anywhere. The Nurse Licensure Compact covers RN and LPN/VN licenses only, so it does not extend APRN practice across state lines.
Does my national certification have to be current to renew my South Carolina APRN license?: Most boards condition the APRN credential on current national certification, so a certification lapse can block state renewal. Confirm South Carolina's exact rule with the South Carolina Board of Nursing before letting any clock run out.

More for South Carolina nurses

Four clocks are too many to keep in your head

Track your RN license, APRN credential, national certification, and DEA registration in one place, free to start.

Start Tracking — Free

Requirement

Hours

Status

APRN Prescriptive Authority Pharmacotherapeutics

20 hrs

Required

Prescriptive authority in South Carolina

• Does prescribing require a collaboration or supervision agreement, and must it be re-filed at renewal?
• Is there a state controlled-substance registration separate from your DEA registration?
• Is there prescriber-specific pharmacology CE beyond the base requirement?
• Is current national certification a condition of APRN renewal?

The other three clocks

South Carolina APRN renewal FAQ

How many CE hours do APRNs need to renew in South Carolina?

APRNs in South Carolina complete 30 CE hours every 2 years for board renewal. That includes the APRN Prescriptive Authority Pharmacotherapeutics requirement of 20 hours. Your national certification keeps its own CE requirement on a separate clock.

What is the APRN renewal fee in South Carolina?

The South Carolina APRN renewal fee is $105, which differs from the RN fee; budget for both if you renew both credentials. Fees change, so confirm the current amount on the South Carolina Board of Nursing portal.

Can APRNs prescribe independently in South Carolina?

Practice-authority rules vary by state and change often. South Carolina's exact collaboration and prescribing rules are set by the South Carolina Board of Nursing; confirm them there before relying on any summary.

Does South Carolina require a state controlled-substance registration on top of the DEA?

Some states require a state controlled-substance registration separate from your federal DEA registration; others do not. South Carolina's rule is set by the board and state law; confirm before prescribing.

Is South Carolina in the APRN Compact?

No. South Carolina has not enacted the APRN Compact, and the compact itself is not yet operational anywhere. The Nurse Licensure Compact covers RN and LPN/VN licenses only, so it does not extend APRN practice across state lines.

Does my national certification have to be current to renew my South Carolina APRN license?

Most boards condition the APRN credential on current national certification, so a certification lapse can block state renewal. Confirm South Carolina's exact rule with the South Carolina Board of Nursing before letting any clock run out.