South Carolina APRN License Renewal: CE, Fees, and Prescriptive Rules

Built by Keegan, a travel RN · verified against official board sources

NP, CRNA, CNM, CNS · Verified against the South Carolina Board of Nursing · 2026-07-13

APRNs in South Carolina complete 30 CE hours every 2 years for board renewal. The APRN renewal fee is $105. The board is one of up to four clocks: your national certification and any DEA registration renew separately.

What the South Carolina Board of Nursing requires of APRNs

Requirement	Hours	Status
APRN Prescriptive Authority Pharmacotherapeutics	20 hrs	Required

Full renewal context (deadlines, grace period, audits): South Carolina nursing license renewal guide.

Prescriptive authority in South Carolina

What we verified for South Carolina

Board-sourced

Practice authority: Restricted-practice model: APRNs prescribe under a written practice agreement with a physician who is readily available for consultation; one physician may cover at most 6 NPs/PAs/CNMs/CNSs. Full-practice bills were pending, not enacted, as of June 2026.
Collaboration / supervision: The practice agreement must be tailored to the APRN's clinical setting and kept current (reviewed and amended as practice changes).
State controlled-substance registration: Yes: South Carolina Bureau of Drug Control registration is required for APRNs prescribing Schedules II to V, issued after the board-approved written protocol, alongside DEA registration.
Prescriber CE: Initial prescriptive authority: 45 pharmacotherapeutics hours within the prior 2 years (at least 15 in controlled substances). Renewal: 20 pharmacotherapeutics hours per 2 years (at least 2 in controlled substances).
National certification at renewal: Yes. National board certification must be maintained current throughout licensure and at each renewal.

Source: South Carolina LLR Board of Nursing, APRN prescriptive authority, last checked 2026-06-11. Rules change; confirm with the board before relying on this.

The other three clocks

South Carolina has not enacted the APRN Compact (which is not yet operational anywhere). The Nurse Licensure Compact covers RN and LPN/VN licenses only, so multi-state APRN practice still means a separate APRN credential in each state. Your national certification (AANPCB, ANCC, NBCRNA, or AMCB) and any DEA registration renew on their own cycles, with their own CE math.

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South Carolina APRN renewal FAQ

How many CE hours do APRNs need to renew in South Carolina?: APRNs in South Carolina complete 30 CE hours every 2 years for board renewal. That includes the APRN Prescriptive Authority Pharmacotherapeutics requirement of 20 hours. Your national certification keeps its own CE requirement on a separate clock.
What is the APRN renewal fee in South Carolina?: The South Carolina APRN renewal fee is $105, which differs from the RN fee; budget for both if you renew both credentials. Fees change, so confirm the current amount on the South Carolina Board of Nursing portal.
Can APRNs prescribe independently in South Carolina?: Restricted-practice model: APRNs prescribe under a written practice agreement with a physician who is readily available for consultation; one physician may cover at most 6 NPs/PAs/CNMs/CNSs. Full-practice bills were pending, not enacted, as of June 2026.
Does South Carolina require a state controlled-substance registration on top of the DEA?: Yes: South Carolina Bureau of Drug Control registration is required for APRNs prescribing Schedules II to V, issued after the board-approved written protocol, alongside DEA registration.
Is South Carolina in the APRN Compact?: No. South Carolina has not enacted the APRN Compact, and the compact itself is not yet operational anywhere. The Nurse Licensure Compact covers RN and LPN/VN licenses only, so it does not extend APRN practice across state lines.
Does my national certification have to be current to renew my South Carolina APRN license?: Yes. National board certification must be maintained current throughout licensure and at each renewal.

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South Carolina APRN License Renewal: CE, Fees, and Prescriptive Rules

NP, CRNA, CNM, CNS · Verified against the South Carolina Board of Nursing · 2026-07-13

Requirement

Hours

Status

APRN Prescriptive Authority Pharmacotherapeutics

20 hrs

Required

Prescriptive authority in South Carolina

What we verified for South Carolina

Board-sourced

Practice authority: Restricted-practice model: APRNs prescribe under a written practice agreement with a physician who is readily available for consultation; one physician may cover at most 6 NPs/PAs/CNMs/CNSs. Full-practice bills were pending, not enacted, as of June 2026.
Collaboration / supervision: The practice agreement must be tailored to the APRN's clinical setting and kept current (reviewed and amended as practice changes).
State controlled-substance registration: Yes: South Carolina Bureau of Drug Control registration is required for APRNs prescribing Schedules II to V, issued after the board-approved written protocol, alongside DEA registration.
Prescriber CE: Initial prescriptive authority: 45 pharmacotherapeutics hours within the prior 2 years (at least 15 in controlled substances). Renewal: 20 pharmacotherapeutics hours per 2 years (at least 2 in controlled substances).
National certification at renewal: Yes. National board certification must be maintained current throughout licensure and at each renewal.

Source: South Carolina LLR Board of Nursing, APRN prescriptive authority, last checked 2026-06-11. Rules change; confirm with the board before relying on this.

The other three clocks

South Carolina APRN renewal FAQ

How many CE hours do APRNs need to renew in South Carolina?

APRNs in South Carolina complete 30 CE hours every 2 years for board renewal. That includes the APRN Prescriptive Authority Pharmacotherapeutics requirement of 20 hours. Your national certification keeps its own CE requirement on a separate clock.

What is the APRN renewal fee in South Carolina?

The South Carolina APRN renewal fee is $105, which differs from the RN fee; budget for both if you renew both credentials. Fees change, so confirm the current amount on the South Carolina Board of Nursing portal.

Can APRNs prescribe independently in South Carolina?

Restricted-practice model: APRNs prescribe under a written practice agreement with a physician who is readily available for consultation; one physician may cover at most 6 NPs/PAs/CNMs/CNSs. Full-practice bills were pending, not enacted, as of June 2026.

Does South Carolina require a state controlled-substance registration on top of the DEA?

Yes: South Carolina Bureau of Drug Control registration is required for APRNs prescribing Schedules II to V, issued after the board-approved written protocol, alongside DEA registration.

Is South Carolina in the APRN Compact?

No. South Carolina has not enacted the APRN Compact, and the compact itself is not yet operational anywhere. The Nurse Licensure Compact covers RN and LPN/VN licenses only, so it does not extend APRN practice across state lines.

Does my national certification have to be current to renew my South Carolina APRN license?

Yes. National board certification must be maintained current throughout licensure and at each renewal.