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Nurse salary data
Built by Keegan, a travel RN · verified against official board sources
The median registered nurse salary in Missouri is $81,780 a year (about $41.30/hour), per the U.S. Bureau of Labor Statistics (May 2025 OEWS). That is about 16% lower than the national median of $97,550, ranking Missouri #40 of 51 for RN pay.
$81,780
Median (annual)
$85,900
Mean (annual)
$41.30
Mean hourly
76,310
RNs employed
These are BLS occupational wage figures for Registered Nurses (SOC 29-1141): averages across all RN settings and experience levels in Missouri, not a starting salary. Pay closely tracks local cost of living, so a higher headline number does not always mean more buying power. Specialty, shift, and years of experience move individual pay well above or below these medians.
Median annual wage for each rung of the Missouri nursing career ladder (BLS OEWS, May 2025). Advancing a rung usually means more schooling and a separate national credential.
| Role | Median pay | |
|---|---|---|
| Licensed Practical Nurse (LPN) | $61,530 | Missouri data |
| Registered Nurse (RN)This page | $81,780 | |
| Nurse Practitioner (NP) | $129,930 | Missouri data |
| Nurse Anesthetist (CRNA) | $242,630 | Missouri data |
The median RN salary in Missouri is $81,780 per year and the mean (average) is $85,900, per the U.S. Bureau of Labor Statistics (May 2025 OEWS). The mean hourly wage is about $41.30.
Missouri's median RN salary of $81,780 is about 16% lower than the national median of $97,550. It ranks #40 of 51 U.S. jurisdictions by median RN pay. Remember that pay tracks cost of living, so a higher number does not always mean more buying power.
Missouri employs about 76,310 registered nurses, per the BLS OEWS May 2025 release.
Among LPNs, RNs, and advanced-practice nurses in Missouri, CRNAs report the highest median pay at $242,630, compared with $81,780 for RNs. Moving up the ladder generally means graduate education and a separate national credential, per BLS OEWS May 2025.
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Source: U.S. Bureau of Labor Statistics, OEWS (Registered Nurses (SOC 29-1141), May 2025 release).