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Nurse salary data
Built by Keegan, a travel RN · verified against official board sources
The median registered nurse salary in South Carolina is $82,360 a year (about $42.15/hour), per the U.S. Bureau of Labor Statistics (May 2025 OEWS). That is about 16% lower than the national median of $97,550, ranking South Carolina #39 of 51 for RN pay.
$82,360
Median (annual)
$87,670
Mean (annual)
$42.15
Mean hourly
49,750
RNs employed
These are BLS occupational wage figures for Registered Nurses (SOC 29-1141): averages across all RN settings and experience levels in South Carolina, not a starting salary. Pay closely tracks local cost of living, so a higher headline number does not always mean more buying power. Specialty, shift, and years of experience move individual pay well above or below these medians.
Median annual wage for each rung of the South Carolina nursing career ladder (BLS OEWS, May 2025). Advancing a rung usually means more schooling and a separate national credential.
| Role | Median pay | |
|---|---|---|
| Licensed Practical Nurse (LPN) | $61,820 | South Carolina data |
| Registered Nurse (RN)This page | $82,360 | |
| Nurse Practitioner (NP) | $123,290 | South Carolina data |
| Nurse Anesthetist (CRNA) | $265,480 | South Carolina data |
The median RN salary in South Carolina is $82,360 per year and the mean (average) is $87,670, per the U.S. Bureau of Labor Statistics (May 2025 OEWS). The mean hourly wage is about $42.15.
South Carolina's median RN salary of $82,360 is about 16% lower than the national median of $97,550. It ranks #39 of 51 U.S. jurisdictions by median RN pay. Remember that pay tracks cost of living, so a higher number does not always mean more buying power.
South Carolina employs about 49,750 registered nurses, per the BLS OEWS May 2025 release.
Among LPNs, RNs, and advanced-practice nurses in South Carolina, CRNAs report the highest median pay at $265,480, compared with $82,360 for RNs. Moving up the ladder generally means graduate education and a separate national credential, per BLS OEWS May 2025.
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Source: U.S. Bureau of Labor Statistics, OEWS (Registered Nurses (SOC 29-1141), May 2025 release).