Mississippi APRN license renewal: CE, fees, and prescriptive rules

NP, CRNA, CNM, CNS · Verified 2026-06-04

APRNs in Mississippi complete 5 CE hours every 2 years for board renewal. The APRN renewal fee is $100. The board is one of up to four clocks: your national certification and any DEA registration renew separately.

What the Mississippi Board of Nursing requires of APRNs

Requirement	Hours	Status
APRN Controlled Substances	5 hrs	Required

Renewal deadlines in Mississippi differ by license type: December 31 of even-numbered years (RN/APRN); December 31 of odd-numbered years (LPN). Renewal period opens September 1.. Confirm your APRN deadline with the board.

Full renewal context (deadlines, grace period, audits): Mississippi nursing license renewal guide.

Prescriptive authority in Mississippi

Practice-authority and prescribing rules are the most state-specific (and fastest-changing) part of APRN practice: collaboration agreements, state controlled-substance registrations, and prescriber CE all vary. We have not yet verified Mississippi's rules against a board source, so confirm these with the Mississippi Board of Nursing before relying on any summary:

• Does prescribing require a collaboration or supervision agreement, and must it be re-filed at renewal?
• Is there a state controlled-substance registration separate from your DEA registration?
• Is there prescriber-specific pharmacology CE beyond the base requirement?
• Is current national certification a condition of APRN renewal?

The other three clocks

Mississippi has not enacted the APRN Compact (which is not yet operational anywhere). The Nurse Licensure Compact covers RN and LPN/VN licenses only, so multi-state APRN practice still means a separate APRN credential in each state. Your national certification (AANPCB, ANCC, NBCRNA, or AMCB) and any DEA registration renew on their own cycles, with their own CE math.

The four-clock guide: certification cycles, compact status, DEA and MATE

Mississippi APRN renewal FAQ

How many CE hours do APRNs need to renew in Mississippi?: APRNs in Mississippi complete 5 CE hours every 2 years for board renewal. Your national certification keeps its own CE requirement on a separate clock.
What is the APRN renewal fee in Mississippi?: The Mississippi APRN renewal fee is $100. Fees change, so confirm the current amount on the Mississippi Board of Nursing portal.
Can APRNs prescribe independently in Mississippi?: Practice-authority rules vary by state and change often. Mississippi's exact collaboration and prescribing rules are set by the Mississippi Board of Nursing; confirm them there before relying on any summary.
Does Mississippi require a state controlled-substance registration on top of the DEA?: Some states require a state controlled-substance registration separate from your federal DEA registration; others do not. Mississippi's rule is set by the board and state law; confirm before prescribing.
Is Mississippi in the APRN Compact?: No. Mississippi has not enacted the APRN Compact, and the compact itself is not yet operational anywhere. The Nurse Licensure Compact covers RN and LPN/VN licenses only, so it does not extend APRN practice across state lines.
Does my national certification have to be current to renew my Mississippi APRN license?: Most boards condition the APRN credential on current national certification, so a certification lapse can block state renewal. Confirm Mississippi's exact rule with the Mississippi Board of Nursing before letting any clock run out.

More for Mississippi nurses

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What the Mississippi Board of Nursing requires of APRNs

Requirement	Hours	Status
APRN Controlled Substances	5 hrs	Required

Prescriptive authority in Mississippi

• Does prescribing require a collaboration or supervision agreement, and must it be re-filed at renewal?
• Is there a state controlled-substance registration separate from your DEA registration?
• Is there prescriber-specific pharmacology CE beyond the base requirement?
• Is current national certification a condition of APRN renewal?

The other three clocks

Mississippi APRN renewal FAQ

How many CE hours do APRNs need to renew in Mississippi?

APRNs in Mississippi complete 5 CE hours every 2 years for board renewal. Your national certification keeps its own CE requirement on a separate clock.

What is the APRN renewal fee in Mississippi?

The Mississippi APRN renewal fee is $100. Fees change, so confirm the current amount on the Mississippi Board of Nursing portal.

Can APRNs prescribe independently in Mississippi?

Practice-authority rules vary by state and change often. Mississippi's exact collaboration and prescribing rules are set by the Mississippi Board of Nursing; confirm them there before relying on any summary.

Does Mississippi require a state controlled-substance registration on top of the DEA?

Some states require a state controlled-substance registration separate from your federal DEA registration; others do not. Mississippi's rule is set by the board and state law; confirm before prescribing.

Is Mississippi in the APRN Compact?

No. Mississippi has not enacted the APRN Compact, and the compact itself is not yet operational anywhere. The Nurse Licensure Compact covers RN and LPN/VN licenses only, so it does not extend APRN practice across state lines.

Does my national certification have to be current to renew my Mississippi APRN license?

Most boards condition the APRN credential on current national certification, so a certification lapse can block state renewal. Confirm Mississippi's exact rule with the Mississippi Board of Nursing before letting any clock run out.