Mississippi APRN License Renewal: CE, Fees, and Prescriptive Rules

Built by Keegan, a travel RN · verified against official board sources

NP, CRNA, CNM, CNS · Verified against the Mississippi Board of Nursing · 2026-06-04

APRNs in Mississippi complete 5 CE hours every 2 years for board renewal. The APRN renewal fee is $100. The board is one of up to four clocks: your national certification and any DEA registration renew separately.

What the Mississippi Board of Nursing requires of APRNs

Requirement	Hours	Status
APRN Controlled Substances	5 hrs	Required

Renewal deadlines in Mississippi differ by license type: December 31 of even-numbered years (RN/APRN); December 31 of odd-numbered years (LPN). Renewal period opens September 1.. Confirm your APRN deadline with the board.

Full renewal context (deadlines, grace period, audits): Mississippi nursing license renewal guide.

Prescriptive authority in Mississippi

What we verified for Mississippi

Board-sourced

Practice authority: Restricted-practice model: all APRNs practice under a formal collaborative agreement with a licensed, unrestricted Mississippi physician practicing in the same area.
Collaboration / supervision: The collaborative agreement is continuous and mandatory; controlled-substance authority additionally requires a 720-hour supervised period (waivable with 6+ months of out-of-state experience).
State controlled-substance registration: No separate state controlled-substance registration; board approval plus DEA registration govern.
Prescriber CE: 5 hours of controlled-substance CE per 2-year certification period for all APRNs.
National certification at renewal: Yes. Current national certification is required for APRN licensure and renewal.

Source: Mississippi Board of Nursing, APRN, last checked 2026-06-11. Rules change; confirm with the board before relying on this.

The other three clocks

Mississippi has not enacted the APRN Compact (which is not yet operational anywhere). The Nurse Licensure Compact covers RN and LPN/VN licenses only, so multi-state APRN practice still means a separate APRN credential in each state. Your national certification (AANPCB, ANCC, NBCRNA, or AMCB) and any DEA registration renew on their own cycles, with their own CE math.

The four-clock guide: certification cycles, compact status, DEA and MATE

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Mississippi APRN renewal FAQ

How many CE hours do APRNs need to renew in Mississippi?: APRNs in Mississippi complete 5 CE hours every 2 years for board renewal. Your national certification keeps its own CE requirement on a separate clock.
What is the APRN renewal fee in Mississippi?: The Mississippi APRN renewal fee is $100. Fees change, so confirm the current amount on the Mississippi Board of Nursing portal.
Can APRNs prescribe independently in Mississippi?: Restricted-practice model: all APRNs practice under a formal collaborative agreement with a licensed, unrestricted Mississippi physician practicing in the same area.
Does Mississippi require a state controlled-substance registration on top of the DEA?: No separate state controlled-substance registration; board approval plus DEA registration govern.
Is Mississippi in the APRN Compact?: No. Mississippi has not enacted the APRN Compact, and the compact itself is not yet operational anywhere. The Nurse Licensure Compact covers RN and LPN/VN licenses only, so it does not extend APRN practice across state lines.
Does my national certification have to be current to renew my Mississippi APRN license?: Yes. Current national certification is required for APRN licensure and renewal.

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Mississippi APRN License Renewal: CE, Fees, and Prescriptive Rules

NP, CRNA, CNM, CNS · Verified against the Mississippi Board of Nursing · 2026-06-04

What the Mississippi Board of Nursing requires of APRNs

Requirement	Hours	Status
APRN Controlled Substances	5 hrs	Required

Prescriptive authority in Mississippi

What we verified for Mississippi

Board-sourced

Practice authority: Restricted-practice model: all APRNs practice under a formal collaborative agreement with a licensed, unrestricted Mississippi physician practicing in the same area.
Collaboration / supervision: The collaborative agreement is continuous and mandatory; controlled-substance authority additionally requires a 720-hour supervised period (waivable with 6+ months of out-of-state experience).
State controlled-substance registration: No separate state controlled-substance registration; board approval plus DEA registration govern.
Prescriber CE: 5 hours of controlled-substance CE per 2-year certification period for all APRNs.
National certification at renewal: Yes. Current national certification is required for APRN licensure and renewal.

Source: Mississippi Board of Nursing, APRN, last checked 2026-06-11. Rules change; confirm with the board before relying on this.

The other three clocks

Mississippi APRN renewal FAQ

How many CE hours do APRNs need to renew in Mississippi?

APRNs in Mississippi complete 5 CE hours every 2 years for board renewal. Your national certification keeps its own CE requirement on a separate clock.

What is the APRN renewal fee in Mississippi?

The Mississippi APRN renewal fee is $100. Fees change, so confirm the current amount on the Mississippi Board of Nursing portal.

Can APRNs prescribe independently in Mississippi?

Restricted-practice model: all APRNs practice under a formal collaborative agreement with a licensed, unrestricted Mississippi physician practicing in the same area.

Does Mississippi require a state controlled-substance registration on top of the DEA?

No separate state controlled-substance registration; board approval plus DEA registration govern.

Is Mississippi in the APRN Compact?

No. Mississippi has not enacted the APRN Compact, and the compact itself is not yet operational anywhere. The Nurse Licensure Compact covers RN and LPN/VN licenses only, so it does not extend APRN practice across state lines.

Does my national certification have to be current to renew my Mississippi APRN license?

Yes. Current national certification is required for APRN licensure and renewal.