Missouri APRN license renewal: CE, fees, and prescriptive rules

NP, CRNA, CNM, CNS · Verified 2026-06-04

The Missouri State Board of Nursing does not set a fixed CE-hour mandate for APRN renewal. The APRN renewal fee is $85. The board is one of up to four clocks: your national certification and any DEA registration renew separately.

What the Missouri State Board of Nursing requires of APRNs

Requirement	Hours	Status
No CE Required	Course-based	Required

Renewal deadlines in Missouri differ by license type: April 30 of odd-numbered years (RN); May 31 of even-numbered years (LPN); APRN tied to certification or RN expiration. Confirm your APRN deadline with the board.

Full renewal context (deadlines, grace period, audits): Missouri nursing license renewal guide.

Prescriptive authority in Missouri

Practice-authority and prescribing rules are the most state-specific (and fastest-changing) part of APRN practice: collaboration agreements, state controlled-substance registrations, and prescriber CE all vary. We have not yet verified Missouri's rules against a board source, so confirm these with the Missouri State Board of Nursing before relying on any summary:

• Does prescribing require a collaboration or supervision agreement, and must it be re-filed at renewal?
• Is there a state controlled-substance registration separate from your DEA registration?
• Is there prescriber-specific pharmacology CE beyond the base requirement?
• Is current national certification a condition of APRN renewal?

The other three clocks

Missouri has not enacted the APRN Compact (which is not yet operational anywhere). The Nurse Licensure Compact covers RN and LPN/VN licenses only, so multi-state APRN practice still means a separate APRN credential in each state. Your national certification (AANPCB, ANCC, NBCRNA, or AMCB) and any DEA registration renew on their own cycles, with their own CE math.

The four-clock guide: certification cycles, compact status, DEA and MATE

Missouri APRN renewal FAQ

How many CE hours do APRNs need to renew in Missouri?: The Missouri State Board of Nursing does not set a fixed CE-hour mandate for APRN renewal. Your national certification still carries its own CE requirement on a separate clock.
What is the APRN renewal fee in Missouri?: The Missouri APRN renewal fee is $85. Fees change, so confirm the current amount on the Missouri State Board of Nursing portal.
Can APRNs prescribe independently in Missouri?: Practice-authority rules vary by state and change often. Missouri's exact collaboration and prescribing rules are set by the Missouri State Board of Nursing; confirm them there before relying on any summary.
Does Missouri require a state controlled-substance registration on top of the DEA?: Some states require a state controlled-substance registration separate from your federal DEA registration; others do not. Missouri's rule is set by the board and state law; confirm before prescribing.
Is Missouri in the APRN Compact?: No. Missouri has not enacted the APRN Compact, and the compact itself is not yet operational anywhere. The Nurse Licensure Compact covers RN and LPN/VN licenses only, so it does not extend APRN practice across state lines.
Does my national certification have to be current to renew my Missouri APRN license?: Most boards condition the APRN credential on current national certification, so a certification lapse can block state renewal. Confirm Missouri's exact rule with the Missouri State Board of Nursing before letting any clock run out.

More for Missouri nurses

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What the Missouri State Board of Nursing requires of APRNs

Requirement	Hours	Status
No CE Required	Course-based	Required

Prescriptive authority in Missouri

• Does prescribing require a collaboration or supervision agreement, and must it be re-filed at renewal?
• Is there a state controlled-substance registration separate from your DEA registration?
• Is there prescriber-specific pharmacology CE beyond the base requirement?
• Is current national certification a condition of APRN renewal?

The other three clocks

Missouri APRN renewal FAQ

How many CE hours do APRNs need to renew in Missouri?

The Missouri State Board of Nursing does not set a fixed CE-hour mandate for APRN renewal. Your national certification still carries its own CE requirement on a separate clock.

What is the APRN renewal fee in Missouri?

The Missouri APRN renewal fee is $85. Fees change, so confirm the current amount on the Missouri State Board of Nursing portal.

Can APRNs prescribe independently in Missouri?

Practice-authority rules vary by state and change often. Missouri's exact collaboration and prescribing rules are set by the Missouri State Board of Nursing; confirm them there before relying on any summary.

Does Missouri require a state controlled-substance registration on top of the DEA?

Some states require a state controlled-substance registration separate from your federal DEA registration; others do not. Missouri's rule is set by the board and state law; confirm before prescribing.

Is Missouri in the APRN Compact?

No. Missouri has not enacted the APRN Compact, and the compact itself is not yet operational anywhere. The Nurse Licensure Compact covers RN and LPN/VN licenses only, so it does not extend APRN practice across state lines.

Does my national certification have to be current to renew my Missouri APRN license?

Most boards condition the APRN credential on current national certification, so a certification lapse can block state renewal. Confirm Missouri's exact rule with the Missouri State Board of Nursing before letting any clock run out.