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Initial licensure by examination · Verified 2026-07-08
To get your first RN license in Missouri, you graduate from an approved nursing program, apply for licensure by examination through the Missouri State Board of Nursing, complete the required background check, and pass the NCLEX-RN. Yes. Missouri requires a fingerprint-based criminal background check to get an initial RN license. Applicants must submit fingerprints (via MACHS registration number 0001 for in-state applicants, or an IdentoGO/local law-enforcement LiveScan or FD-258 card for out-of-state applicants) for a joint Missouri State Highway Patrol and FBI criminal background check; 20 CSR 2200-4.020(1)(E) also states the applicant "shall submit to state and federal fingerprint or other biometric criminal background checks."
Source: Missouri State Board of Nursing, last checked 2026-07-08. Fees and rules change; confirm with the board before you rely on a figure.
Start at the source: Missouri State Board of Nursing. Already licensed elsewhere and moving to Missouri? See licensure by endorsement instead.
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